Pharmaceutical Intermediates 2

List of Intermediates

Alogliptin Intermediates		Anti Diabetic
2-[(6-chloro-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl)methyl]-Benzonitrile	865758-96-9
(R)-3-(Boc-Amino)piperidine	309956-78-3
Apixaban Intermediates		Anti Coagulant
1-(4-Iodophenyl)-3-morpholino-5,6-dihydropyridine-2(1H)-one	473927-69-4
Chloro[(4-methoxy phenyl)hydrazono]acetic acid ethyl ester	27143-07-3
4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester	503614-91-3
3-morpholino-1-(4-(2-oxopiperidin-1-yl)-5,6-dihydropiperidine-2(1H)-one	545445-44-1
Ethyl 6-(4-Iodophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate	473927-64-9
Canagliflozin Intermediate		Anti Diabetic
2,3,4,6-Tetrakis-O-(trimethylsilyl)D-glocono 1,5-lactone	32384-65-9
2-(5-Bromo-methyl Benzyl)-5-(4-fluorophenyl)thiophene	1030825-20-7
(2R,3R,4S,5S,6R)-2-(3-((5-(4-Fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)-tetrahydro-6-(hydromethyl)-2-methoxy-2H-pyran-3,4,5-triol	----------------
Cyclam
1,4,8,11-Tetraazacyclotetradecane	295-37-4
Dabigatran Intermediates		Anti Coagulant
2-[(4-Cyanophenyl)amino]acetic acid	42288-26-6
Ethyl N-[3-amino-4-(methylamino)benzoyl]-N-pyridin-2-yl-B-alaninate	212322-56-0
Ethyl 3-(2-((4-cyanophenylamino)methyl)-1-methyl-N-(pyridine-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate	211915-84-3
Dapagliflozin intermediates		Anti Diabetic
2,3,4,6-Tetrakis-O-(trimethylsilyl)D-glocono 1,5-lactone	32384-65-9
5-Bromo-2-chloro-4-ethoxydiphenylmethane	461432-23-5
(2S,3R,4S,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol	----------------
Dex pramipexole/Pramipexole Intermediates		Anti Parkinsonian
(S)-(-)-2,6-Diamino-4,5,6,7-tetrahydro benzothizole	106092-09-5
(R)-(+)-2,6-Diamino-4,5,6,7-tetrahydro benzothizole	106092-11-9
±-2,6-Diamino-4,5,6,7-tetrahydro benzothizole	104617-49-4

Linagliptin Intermediates		Anti Diabetic
2-(Chloromethyl)-4-methylquinazoline	109113-72-6
8-Bromo-3-methyl-1H-purine-2,6-(3H,7H)-dione	93703-24-3
8-Bromo-7-(but-2-yn-1-yl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione	666816-98-4
(R)-3-(Boc-Amino)piperidine	309956-78-3
(R)-3-Amino piperidine dihydrochloride	334618-23-4
(R)-3-N-CBZ-Amino piperidine	478646-32-1
(1-[(4-methylquinazoline-2-yl-)methyl]-3-methyl-7-(2-butyn-1-yl)-8-bromaxanthine)	853029-57-9
Luliconazole Intermediates	187164-19-8	Anti Fungal
(S)-2-chloro-1-(2,4-dichlorophenyl)ethyl methanesulfonate	229334-55-8
1-(Cyanomethyl)Imidazole	98873-55-3
Lurasidone Intermediates		Anti Psychotic
3-(1-piperazinyl)-1,2-benzisothiazole	87691-87-0
(1R,2R)-1,2-Cyclohexanedimethanol	65376-05-8
(3aR,4S,7R,7aS)4,7-Methano-1H-Isoindole-1,3-(2H)-dione	14805-29-9
Mirabegron Intermediates		Anti Muscarinic
(R)-N-(4-Nitrophenethyl)-2-hydroxy-2-phenyl acetamide	521284-19-5
(R)-2-(4-Nitrophenethylamino)-1-phenylethanol hydrochloride	----------------
Pralatrexate Intermediates		Anti Cancer
2,4-Diamino-6-(hydroxymethyl)pteridine.HCL	73978-41-3
Methyl 4-(1-(methoxycarbonyl)but-3-ynyl)benzoate	146464-90-6
Methyl 4-(2-methoxycarbonyl)-1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl)benzoate	146464-91-7
Benzoic acid,4-[1-[(2,4-diamino-6-pteridinyl)methyl]-3-butyn-1-yl	146464-93-9
Ravuconazole Intermediates		Anti Fungal
1-[[(2R,3S)-2-(2,4-Diflorophenyl)-3-methyloxiranyl])methyl]-1H-1,2,4-triazole	127000-90-2
Tofacitinib/Tasocitinib Intermediates		Rheumatoid Arthristis
Cis-N-Benzyl-3-methyl amino-4-methyl piperidine-Bis hydrochloride	-----------------
4-Chloro-7-tosyl-7H-pyrrolo[2,3,-a]pyrimidine	479633-63-1
N-Methyl-N-(3R,4R)-4-methylpiperidin-3yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine	477600-74-1
Bis[(3R,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine]di-p-toluyl-L-tartrate	477600-71-8

Ticagrelor Intermediates		Anti Thrombotic
4,6-Dichloro-5-nitro-2-(propylthio)pyrimidine	145783-14-8
(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine	220352-38-5
2-{[(3aR,4S,6R,6aS)-6-amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]-dioxol-4-yl]oxy}-1-ethol	274693-55-9
Vilazodone Intermediates		Anti Depressant
5-(1-Piperazinyl)-1-benzofuran-2-carboxamidehtdrochloride	183288-46-2
3-(4-Chlorobutyl)-1H-Indole-5-carbonitrile	143612-79-7

API Intermediates Under Development

Lanoconazole Intermediates		Anti Fungal
1-(Cyanomethyl)imidazole	361442-00-4
2-Chloro-1-(2-chlorophenyl)ethyl methane sulfonate
Perampanel Intermediates		Anti Epileptic
5-(Pyridin-2-yl)pyridin-2(1H)-one	98873-55-3
1-Phenyl-5-(pyridin-2-yl) pyridin-2(1H)-one	-----------------
3-Bromo-1-phenyl-5-(pyridin-2-yl) pyridin-2(1H)-one	-----------------
5’-(2-Cyanophenyl)-1’-phenyl-2,3’-bipyridinyl-6’(1’H)-one	380971-97-5
Saxagliptin Intermediates		Anti Diabetic
Boc-3-Hydroxy-1-adamantyl-D-glycine	361442-00-4
(1S,3S,5S)-3-(Aminocarbonyl)-2-azabicyclo[3,1,0]hexane-2-carboxylic acid tert-butyl ester	361440-67-7